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Increasing infection testing types to Truenat technology. In current years, Molbio Diagnostics’ Truenate technology has revolutionized the field of molecular diagnostics in India. In an exclusive interview with Financial Express.com, Sriram Natarajan, Director, and CEO of Molbio Diagnostics said truncate technology with point-of-care capabilities has enhanced infectious disease diagnostic capabilities.

RT-PCR – the most reliable and best technique

Everyone knew that RT-PCR was the most reliable and best technique for diagnosing disease, but due to its highly centralized nature, it was not used as a routine parameter. I never did. Biotech Labs is his R&D department at Molbio, which he collaborated with to conceptualize this. It took about 12 years before the first prototype was ready for sale. After that, it took me another 4-5 years to get to my current level. Today, tests for about 40 diseases can be performed. The goal of getting it to people is working now, and we’re happy with it, he told Financial Express.com.

In July 2020, the World Health Organization (WHO) approved three molecules, Truenate MTB, Truenate MTB Plus, and Truenate MTB-RIF Dx, for the initial diagnosis of tuberculosis (TB) in adults and subsequent detection of rifampicin resistance. Approved Rapid Authenticity Test. Children with signs and symptoms of pulmonary tuberculosis.

Both Truenat MTB and Truenat MTB Plus detect Mycobacterium tuberculosis for tuberculosis diagnosis. Truenat MTB-RIF Dx, on the other hand, identifies resistance to the most commonly used first-line treatment, rifampicin.

In a 2020 press release, the Indian Council for Medical Research (ICMR) conducted a proof-of-concept under a national program after conducting multi-center validation of the Truenate MTB and Truenate MTB-RIF Dx assays, demonstrating that they demonstrate sensitivity and Comparable to the internationally recognized Xpert MTB/RIF molecular assay (Cepheid, Sunnyvale, USA) in terms of specificity and detection of rifampicin resistance.

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